We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
The Evaluation of Troponin I Levels and Myocarditis in Children with COVID-19: A Pediatric Single-Center Experience.
- Authors
Guner Ozenen, Gizem; Akaslan Kara, Aybuke; Kiymet, Elif; Boncuoglu, Elif; Sahinkaya, Sahika; Cem, Ela; Yilmaz Celebi, Miray; Kacar, Pelin; Gulderen, Mustafa; Uras, Meltem; Yılmazer, Murat Muhtar; Murat, Mehmet; Mese, Timur; Agin, Hasan; Bayram, Nuri; Devrim, İlker
- Abstract
Children with COVID-19 usually show milder symptoms than adults; however, a minority of them may have cardiac involvement. We aimed to identify the role of troponin I levels that may predict early cardiac involvement in children with COVID-19. A single-center retrospective study was conducted to evaluate hospitalized children diagnosed with COVID-19 between March 11, 2020, and December 31, 2021. Patients with available troponin I levels and with no known cardiac disease were included. During the study period, 412 children with COVID-19 who had troponin I levels on admission were identified. Troponin levels were elevated in 7 (1.7%) patients and were normal in 395 (98.3%) patients. The median age of patients with elevated troponin levels was 4 (min. 2–max. 144) months, which was statistically lower than the age of patients with normal troponin levels (P = 0.035). All the patients with elevated troponin levels had tachycardia. Out of 7 patients with high troponin levels, 3 (42.9%) of them were admitted to the pediatric intensive care unit (PICU), 2 (28.6%) required oxygen support, and 1 (14.3%) required a mechanical ventilator. Patients with elevated troponin levels had a statistically longer hospital stay (P < 0.001). Neutropenia, tachycardia, PICU admission, oxygen support, and mechanical ventilation were statistically more common in patients with elevated troponin levels (P values were 0.033, 0.020, < 0.001, 0.050, and < 0.001, respectively). Electrocardiography (ECG) and echocardiography (ECHO) were performed on all patients with elevated troponin levels, and 6 (85.8%) patients were diagnosed with myocarditis. The ECG and ECHO have been performed in 58 (14.3%) out of 405 patients with normal troponin levels. Two (3.5%) patients had negative T waves on ECG, and all ECHOs were normal. Our results suggest that elevated troponin I levels in children with COVID-19 can be used to evaluate cardiac involvement and decide the need for further pediatric cardiologist evaluation.
- Subjects
TROPONIN I; CRITICALLY ill; PEDIATRIC intensive care; COVID-19; MYOCARDITIS; HOSPITAL care of children
- Publication
Pediatric Cardiology, 2023, Vol 44, Issue 4, p873
- ISSN
0172-0643
- Publication type
Article
- DOI
10.1007/s00246-022-03017-5