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- Title
Calcaneus bone mineral density in Japanese women with rheumatoid arthritis.
- Authors
Doi, S.; Kushida, K.; Miyamoto, S.; Sekioka, Y.; Suzuki, M.; Inoue, T.; Nagano, A.
- Abstract
Objectives: The aim of this study was to investigate the relationships among bone mineral densities (BM D) in the calcaneus and leg activity of daily living (L-ADL) in rheumatoid arthritis (RA) patients. Methods: We measured and compared calcaneus BM D using single X-ray absorptiometry and lumbar spine and femoral neck BMD using dual X-ray absorptiometry in 158 Japanese female outpatients with RA and 358 normal controls (NC). Results: Regardless of whether the women were premenopausal or postmenopausal, calcaneus and femoral neck BMDs in the RA group were significantly lower than in the NC group. Calcaneus BMD correlated with the modified health assessment questionnaire, L-ADL score, and 10-m walking time, regardless of whether the patients were premenopausal or postmenopausal (P < 0.01). Conclusions: We conclude that calcaneus BMD reflects the L-ADL of RA patients very well and allows us to perform the same level of BMD evaluation as that with current BMD measure- ment methods. increase in fractures in RA patients, which markedly affects their daily activities and quality of life. Therefore, a simpler method is needed to evaluate bone mineral density (BMD) which will allow for mass screening of osteoporosis in RA patients. Looking for such a meth- od, we focused on the calcaneus, a weight-bearing, highly cancellous bone that is less affected by bone fracture. We measured its BMD using single X-ray absorptiometry (SXA) and that of the lumbar spine and femoral neck using dual X-ray absorptiometry (DXA) to compare and investigate how daily life activity, espe- cially lower limb activity, and corticosteroid drug usage affect bone decrease in RA patients.
- Subjects
HEEL bone; RHEUMATOID arthritis; MINERALS in the body; BONE injuries; ARTHRITIS; DISEASES in women
- Publication
Rheumatology International, 2005, Vol 25, Issue 3, p195
- ISSN
0172-8172
- Publication type
Article
- DOI
10.1007/s00296-003-0421-1