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- Title
Polyphenols vs. Coronaviruses: How Far Has Research Moved Forward?
- Authors
Piccolella, Simona; Crescente, Giuseppina; Faramarzi, Shadab; Formato, Marialuisa; Pecoraro, Maria Tommasina; Pacifico, Severina; Cotelle, Philippe
- Abstract
The epidemic, caused by SARS-CoV-2 at the beginning of 2020, led us to a serious change in our lifestyle that for about three months has confined us to our homes, far from our laboratory routine. In this period, the belief that the work of a researcher should never stop has been the driving force in writing the present paper. It aims at reviewing the recent scientific knowledge about in vitro experimental data that focused on the antiviral role of phenols and polyphenols against different species of coronaviruses (CoVs), pointing up the viral targets potentially involved. In the current literature scenario, the papain-like and the 3-chymotrypsin-like proteases seem to be the most deeply investigated and a number of isolated natural (poly)phenols has been screened for their efficacy.
- Subjects
POLYPHENOLS; CORONAVIRUSES; SCIENTIFIC knowledge; PLANT polyphenols; NATURAL numbers; SARS-CoV-2
- Publication
Molecules, 2020, Vol 25, Issue 18, p4103
- ISSN
1420-3049
- Publication type
Article
- DOI
10.3390/molecules25184103