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- Title
Magnetic resonance spectroscopy and <sup>13</sup>C metabolic modeling right under your nose!
- Authors
Henry, Pierre‐Gilles
- Abstract
This article discusses the use of magnetic resonance spectroscopy (MRS) to study the olfactory bulb in rats. The olfactory bulb has been relatively understudied in MRS research, despite its involvement in various pathologies. The study conducted by Chowdhury et al. used 1H and 1H(13C) MR spectra to measure metabolic rates in the olfactory bulb using a three-compartment model. The authors found that the measurement of GABA concentration using J-editing was more precise than short-TE spectra. The study also focused on improving the precision and accuracy of measured metabolic rates by increasing the amount of information in the data being fitted. Overall, this research provides valuable insights into the metabolic processes in the olfactory bulb and opens the door for further improvements in the model.
- Subjects
NUCLEAR magnetic resonance spectroscopy; METABOLIC models; GABAERGIC neurons; OLFACTORY bulb
- Publication
NMR in Biomedicine, 2024, Vol 37, Issue 6, p1
- ISSN
0952-3480
- Publication type
Article
- DOI
10.1002/nbm.5156