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- Title
Indicaciones inhabituales de trasplante hepático. Resultados.
- Authors
T., Andrés Troncoso; V., Eduardo Briceño; M., Alejandra Cancino; M., Paulina Dellepiane; B., Humberto Soriano; A., Juan Gana; G., Carlos Benítez; R., Rodrigo Wolff; M., Francisco Barrera; R., Rodrigo Montaña; P., Mario Concha; S., Juan Carlos Pattilo; C., Nicolás Jarufe; C., Juan Francisco Guerra; M., Martin Dib; C., Jorge Martínez
- Abstract
Introduction: Liver transplantation (LT) is an established therapy in the treatment of several acute and chronic end-stage liver diseases and hepatocellular carcinoma (HCC). The main indications worldwide are cirrhosis of different etiologies, HCC, biliary atresia in children, and fulminant hepatic failure (FHF). Less than 10% concerns unusual indications which include patients with miscellaneous diseases among which are hepatic polycystic disease (HPD), metabolic diseases (Niemann-Pick, others), portal/hepatopulmonary syndrome, metastasis of different tumors, among others. Aim: The objective of the study is to describe and asses the results obtained with liver transplantation in these indications. Materials and Method: We performed a non-concurrent cohort study that included all LT due to unusual indications between March 1997 and December 2016 in a university medical center. Of 295 TH performed, 34 (11.75%) were due to these indications. Results: The most frequent causes were the portal/hepatopulmonary syndrome in 11 (40.7%) patients and HPD in 9 (26.5%). Metabolic diseases accounted for the third indication in 5 (14.7%) cases. Seven (20.6%) patients were less than 18 years old. The most frequent complications were biliary and hepatic artery thrombosis (HAT) in 6 (17.6%) and 4 (11.8%) cases, respectively. Patients complicated by a HAT suffered a massive EPH. Four (12.5%), required retransplantation. Mortality at 90 days was 2 (5.9%). Conclusion: LT is a feasible option in this group of patients with results similar to those obtained in classic indications of LT.
- Publication
Revista de Cirugia, 2020, Vol 72, Issue 6, p516
- ISSN
2452-4557
- Publication type
Article
- DOI
10.35687/s2452-45492020006686