We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Brain Magnetic Resonance Spectroscopy Findings in the Stroke-like Migraine Attacks after Radiation Therapy (SMART) Syndrome.
- Authors
Gómez‐Cibeira, Emilio; Calleja‐Castaño, Patricia; Gonzalez de la Aleja, Jesus; Sierra‐Hidalgo, Fernando; Ruiz Morales, Juan; Salvador‐Alvarez, Elena; Ramos‐Gonzalez, Ana
- Abstract
A 41-year-old male presented with an acute onset of headache, confusion, seizures, and unilateral focal neurological deficit 25 years after receiving whole-brain radiation therapy to treat a cerebellar medulloblastoma. Brain magnetic resonance imaging (MRI) demonstrated a thick unilateral parieto-occipital cortical contrast enhancement. A diagnosis of "Stroke-like Migraine Attacks after Radiation Therapy" (SMART) syndrome was made. Here, we describe the brain MR spectroscopy findings of SMART, showing a decrease in N-acetyl-aspartate and increased levels of creatine and choline, corresponding with neuronal destruction or transient neuronal impairment with mild nonspecific gliosis. The absence of a lactate peak suggests that mitochondrial dysfunction, vasospasm or ischemic mechanisms were not involved.
- Publication
Journal of Neuroimaging, 2015, Vol 25, Issue 6, p1056
- ISSN
1051-2284
- Publication type
journal article
- DOI
10.1111/jon.12227