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- Title
Rectal Enema Multi Strain Probiotic Therapy Might Mitigate Pruritus, Dermatology Triage and Diamine Oxidase Levels Among Dogs with Food Allergy: Cohort Study.
- Authors
URAL, Kerem
- Abstract
Objective: The incidence and spatial distribution of allergic diseases are significantly increasing in university practice along with field conditions. Increased plasma levels of histamine and diminished diamine oxidase (DAO) activity have been explored as biomarkers of deduced histamine catabolism. Given histamine participates in allergic inflammation, recent data presented the beneficial efficacy of probiotics for combatting. In the present study the aim was to determine the efficacy of rectal enema multi-strain probiotic chain treatment against food allergy (FA) and relevant clinical signs. Material and Methods: In a total of 8 dogs' diagnosis of FA was based on i) history, ii) clinical signs and iii) adopting a trial diet with low carbohydrate. Demographic data involved breed, triage level of pruritus (black color coded severe pruritus, whereas red and green denoted: moderate and minor itching behaviour). DAO levels were determined by use of dog specific test kits via ELISA. Results: At the end of a 10 days trial of rectal enema multi-strain probiotic treatment both pruritus scores and tirage levels were diminished. Mean blood DAO levels (ng/mL) of circulating values were comperatively addicted to before and after treatment (5 vs. 12). Besides DAO levels were significantly increased at day 10 analytes, in contrast to day 0 initial values. Rectal enema multi-strain probiotic treatment was well tolerated without any adverse effects. Conclusion: It was strictly suggested that rectal enema multi-strain probiotic therapy could i) lower pruritus scores and alter triage colors, ii) increase DAO levels in dogs with FA.
- Subjects
ENEMA; PROBIOTICS; ITCHING; DIAMINES; FOOD allergy
- Publication
Türkiye Klinikleri Journal of Veterinary Sciences, 2024, Vol 15, Issue 1, p9
- ISSN
1309-6907
- Publication type
Article
- DOI
10.5336/vetsci.2023-96091