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- Title
Development of the cotton rat ( Sigmodon hispidus) as a biomonitor of environmental contamination with emphasis on hepatic cytochrome P-450 induction and population characteristics.
- Authors
Elangbam, Chandikumar; Qualls, Charles; Lochmiller, Robert; Novak, Joe
- Abstract
The article presents a study which develops a method that will determine the environmental toxicity hazards in human and animals by evaluating hepatic cytochrome P-450 levels in wild cotton rats. The study included the organ pathology and the population characteristics for toxicological evaluation. The study used student's t-test to analyze the cytochrome P-450 values and the significance of organ weights. Results show that male cotton rats revealed 122% means and 119% of control (CS) values.
- Subjects
CYTOCHROME P-450; COTTON rats as laboratory animals; T-test (Statistics); ENVIRONMENTAL toxicology; PATHOLOGY; POPULATION
- Publication
Bulletin of Environmental Contamination & Toxicology, 1989, Vol 42, Issue 4, p482
- ISSN
0007-4861
- Publication type
Article
- DOI
10.1007/BF01700225