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- Title
Diagnosis of Lymphatic Filariasis Using Immunochromatography and Microscopy in Three Local Government Areas of Cross River State, Nigeria.
- Authors
Maurice, M.; Sode, E. U.; Otu-Bassey, I. B.
- Abstract
Human Lymphatic filariasis (LF) caused by three types of filarial worms; Wuchereria bancrofti, Brugia malayi and Brugia timori is one of the neglected tropical diseases and spread by bites of infected Anopheles, Culex, Aedes, Ochleratus and Mansoni mosquitoes. The study evaluated diagnostic methods using blood samples from 420 consented participants in three Local Government Areas of Cross River State. Blood samples were examined following one hour of administration of Diethylcarbamazine citrate for LF microfilaria microscopy (Knott’s concentration) and for LF antigen using immunochromatographic (ICT) method (Alere filariasis test strip). Of the 420 samples examined, 1.7% was found to be positive using microscopy while 4.8% were positive using ICT. There was no significant difference in the diagnosis of lymphatic filariasis using microscopy and ICT among participants in the local government areas (χ2= 21.84, p>0.05). Of the 214 males and 206 females examined, 4.2% males and 5.3% females tested positive using ICT while 1.4% males and 1.9% females were found positive using microscopy. The difference in the infection between gender was statistically significant (χ2=0.298, p<0.05). Participants aged 21-24 years had the highest prevalence of 19.4% while the least prevalence of 1.5% was observed among age group 9-12years using ICT. Also, no significant difference was observed in the diagnosis of LF among the age groups (χ2= 19.88, p>0.05). The study showed that LF still remains a public health problem in Cross River State. Mass drug administration should be scaled up in the state so as to reduce and finally eradicate the disease.
- Subjects
FILARIASIS; FILARIAL worms; BRUGIA malayi; BRUGIA; MICROSCOPY
- Publication
Nigerian Journal of Parasitology, 2020, Vol 41, Issue 2, p173
- ISSN
1117-4145
- Publication type
Article
- DOI
10.4314/njpar.v41i2.8