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- Title
The Serum Corticosteron Levels Alteration in Occlusal Disharmony.
- Authors
Suhartini; Joewarini, Endang; Narmada, Ida Bagus
- Abstract
Introduction: A disturbance in any component of stomatognatic system such as reduced occlusal contacts of teeth will cause occlusal disharmony. Occlusal disharmony identified as stressors that affect homeostasis in the body, particulary in regulatory of corticosterone hormone. The aim of this study was to analyze the levels of corticosterone in the serum of rats with occlusal disharmony. Methods: There were 5 adult male Sprague dawley rats for each group. The occlusal disharmony group and the no treatment (control) group. In the occlusal disharmony group, all of molar cusps were cut off (occlusal grinding) ± 1 mm with fissure bur. The blood samples in heparinized tubes were received from infraorbital vein of rats in each group at 1st day, 7th day, 14th day and 21st. Serum samples were separated by centrifugation. Levels of serum corticosterone were determined using a highly sensitive ELISA kit. Results: There were significant differences of corticosterone serum levels between groups (p <0.05). Tukey HSD test showed that were significant differences between the treatment and control of 1st day and the treatment group on 7th day (p <0.05). Conclusion: This study showed there was alteration of serum corticosterone levels in the serum of rat with occlusal disharmony.
- Subjects
SPRAGUE Dawley rats; SERUM; CORTICOSTERONE
- Publication
Malaysian Journal of Medicine & Health Sciences, 2019, Vol 15, p43
- ISSN
1675-8544
- Publication type
Article