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- Title
The Effect of Preoperative Marijuana Use on Surgical Outcomes, Patient-Reported Outcomes, and Opioid Consumption Following Lumbar Fusion.
- Authors
D'Antonio, Nicholas D.; Lambrechts, Mark J.; Heard, Jeremy C.; Siegel, Nicholas; Karamian, Brian A.; Huang, Angela; Canseco, Jose A.; Woods, Barrett; Kaye, Ian David; Hilibrand, Alan S.; Kepler, Christopher K.; Vaccaro, Alexander R.; Schroeder, Gregory D.
- Abstract
Study Design: Retrospective Cohort Study. Objectives: To (1) investigate the effect of marijuana use on surgical outcomes following lumbar fusion, (2) determine how marijuana use affects patient-reported outcomes measures (PROMs), and (3) determine if marijuana use impacts the quantity of opioids prescribed. Methods: Patients > 18 years of age who underwent primary one- or two-level lumbar fusion with preoperative marijuana use at our institution were identified. A 3:1 propensity match incorporating patient demographics and procedure type was conducted to compare preoperative marijuana users to non-marijuana users. Patient demographics, surgical characteristics, surgical outcomes (90-day all-cause and 90-day surgical readmissions, reoperations, and revision surgeries), pre- and postoperative narcotic usage, and PROMs were compared between groups. Multivariate regression models were created to determine the effect of marijuana on surgical reoperations patient-reported outcomes (PROMs) 1-year postoperatively. Results: Of the 259 included patients, 65 used marijuana preoperatively. Multivariate logistic regression analysis demonstrated that marijuana use (OR = 2.28, P =.041) significantly increased the likelihood of having a spine reoperation. No other surgical outcome was found to be significantly different between groups. Multivariate linear regression analysis showed that marijuana use was not significantly associated with changes in 1-year postoperative PROMs (all, P >.05). The quantity of pre- and postoperative opioids prescriptions was not significantly different between groups (all, P >.05). Conclusions: Preoperative marijuana use increased the likelihood of a spine reoperation for any indication following lumbar fusion, but it was not associated with 90-day all cause readmission, surgical readmission, the magnitude of improvement in PROMs, or differences in opioid consumption. Level of Evidence: III
- Subjects
PATIENT reported outcome measures; MARIJUANA; SPINAL surgery; LOGISTIC regression analysis; SPINAL fusion; OPIOIDS; REOPERATION
- Publication
Global Spine Journal, 2024, Vol 14, Issue 2, p568
- ISSN
2192-5682
- Publication type
Article
- DOI
10.1177/21925682221116819