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- Title
Ethnic Differences in Cerebral Venous Thrombosis.
- Authors
Sá de Camargo, Érica Cristina; Massaro, Ayrton Roberto; Bacheschi, Luiz Alberto; D'Amico, Élbio Antônio; Villaça, Paula Ribeiro; Bassitt, Rogério Pastore; Gualandro, Sandra Fátima; Bendit, Israel; Scaff, Milberto
- Abstract
Background: Cerebral venous thromboses (CVT) with distinct clinical presentations have been shown worldwide. However, there is little information regarding race-ethnic differences in this disease. Methods: We prospectively studied 50 CVT patients from Brazil, comparing clinical and laboratory data among white (W) and African-Brazilian (AB) patients. Results: Seventy percent of the patients were female, 26 W and 23 AB, mean age 34.7 years. Multiple sinus CVT, deep CVT and worse outcome were significantly more frequent in AB than in W patients. There was a trend towards a higher frequency of factor V Leiden and prothrombin mutation in W than in AB, and of protein C deficiency in AB. Conclusions: CVT was more severe in AB patients than in W patients. Race-ethnic differences may account for the heterogeneous distribution of inherited thrombophilia in this series. Copyright © 2005 S. Karger AG, Basel
- Subjects
VENOUS thrombosis; ETHNIC groups; RACIAL differences; BRAIN diseases; VEIN diseases
- Publication
Cerebrovascular Diseases, 2005, Vol 19, Issue 3, p147
- ISSN
1015-9770
- Publication type
Article
- DOI
10.1159/000083247