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- Title
Doxycycline and Sitafloxacin Combination Therapy for Treating Highly Resistant Mycoplasma genitalium.
- Authors
Durukan, Duygu; Doyle, Michelle; Murray, Gerald; Bodiyabadu, Kaveesha; Vodstrcil, Lenka; Chow, Eric P. F.; Jensen, Jorgen S.; Fairley, Christopher K.; Aguirre, Ivette; Bradshaw, Catriona S.
- Abstract
Antimicrobial-resistant Mycoplasma genitalium is becoming increasingly common and creating major treatment challenges. We present early data on combination therapy with doxycycline and sitafloxacin to treat highly resistant M. genitalium. We found the regimen was well tolerated and cured 11/12 infections that had failed prior regimens with moxifloxacin and pristinamycin.
- Subjects
ANTIBIOTICS; MYCOPLASMA; RESEARCH; MYCOPLASMA diseases; RESEARCH methodology; DOXYCYCLINE; MEDICAL cooperation; EVALUATION research; COMPARATIVE studies; DRUG resistance in microorganisms; QUINOLONE antibacterial agents; MACROLIDE antibiotics; PHARMACODYNAMICS
- Publication
Emerging Infectious Diseases, 2020, Vol 26, Issue 8, p1870
- ISSN
1080-6040
- Publication type
journal article
- DOI
10.3201/eid2608.191806