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- Title
Synthesis and Evaluation of azetidin derivatives as antimicrobial activity.
- Authors
Sharma, M. C.
- Abstract
Present communication deals with the synthesis of a novel series of compounds embracing azetidin nucleus in their molecular architecture. The compounds were synthesized in excellent yields and their structures were corroborated on the basis of IR, NMR, Mass analyses data. Moreover, the antimicrobial potential of synthesized compounds was tested against a panel of fungi. It also emphasizes the domination of steric properties over the volumetric properties for modeling the activity against specific type of bacteria. All the synthesized compounds have been found to delineate profound antimicrobial potency as compared to reference drug.
- Subjects
ANTI-infective agents; AZETIDINE; INFRARED radiation; NUCLEAR magnetic resonance; FUNGI
- Publication
International Journal of Pharmacy & Life Sciences, 2017, Vol 8, Issue 11, p17
- ISSN
0976-7126
- Publication type
Article