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- Title
Cyclooxygenase-2 Expression and its Relationship with Proliferation of Colorectal Adenomas.
- Authors
Sato, Takanobu; Yoshinaga, Keigo; Okabe, Satoshi; Okawa, Takuya; Higuchi, Tetsuro; Enomoto, Masayuki; Takizawa, Touichirou; Sugihara, Kenichi
- Abstract
Background: Cyclooxygenase (COX)-2 may be linked to carcinogenesis. In the previous study, we examined COX-2 expression immunohistochemically in 95 adenomas and reported a significant correlation between its expression and the grade of dysplasia. To clarify the correlation between COX-2 expression and cell proliferation, we investigated Ki-67 labeling index using immunohistochemistry and its correlation with COX-2 expression.
- Publication
Japanese Journal of Clinical Oncology, 2003, Vol 33, Issue 12, p631
- ISSN
0368-2811
- Publication type
Article
- DOI
10.1093/jjco/hyg114