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- Title
Splenic Marginal Zone Lymphoma with Prominent Myelofibrosis Mimicking Triple-Negative Primary Myelofibrosis.
- Authors
Tsutsui, Miyuki; Yasuda, Hajime; Ota, Yasunori; Komatsu, Norio
- Abstract
Myelofibrosis (MF) can occur due to a wide variety of causes including malignant lymphoma. We report a case of splenic marginal zone lymphoma complicated by MF mimicking primary myelofibrosis (PMF). The JAK2, CALR and MPL mutations are detected in more than 90% of PMF cases, and when detected, the diagnosis of PMF is usually straight forward. Mutational analysis should be done in all cases of MF, and in triple-negative cases, an exhaustive investigation of other causes of MF should be carried out before a diagnosis of triple-negative PMF is rendered.
- Subjects
LYMPHOMAS; MYELOFIBROSIS; ZONING
- Publication
Case Reports in Oncology, 2019, Vol 12, Issue 3, p834
- ISSN
1662-6575
- Publication type
Article
- DOI
10.1159/000504129