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- Title
Early kinetics of cellular immunity in recipients of bivalent BNT162b2 vaccine: a proof-of-concept study.
- Authors
Salvagno, Gian Luca; Pighi, Laura; Henry, Brandon M.; De Nitto, Simone; Plebani, Mario; Lippi, Giuseppe
- Abstract
Keywords: antibodies; COVID-19; immunity; interferon gamma release assay; SARS-CoV-2; vaccination EN antibodies COVID-19 immunity interferon gamma release assay SARS-CoV-2 vaccination e172 e174 3 07/18/23 20230801 NES 230801 To the Editor, There is now incontrovertible evidence that the accurate characterization of immunity against various pathogens such as the severe acute respiratory syndrome coronavirus disease 2 (SARS-CoV-2) should encompass the assessment of both humoral and cellular immunity, whereby T cell response plays a vital, irreplaceable role in preventing the risk of developing severe forms of coronavirus disease 2019 (COVID-19) [[1]]. Prior vaccination enhances immune responses during SARS-CoV-2 breakthrough infection with early activation of memory T cells followed by production of potent neutralizing antibodies. Antibodies, COVID-19, immunity, interferon gamma release assay, SARS-CoV-2, vaccination.
- Subjects
CELLULAR immunity; SARS-CoV-2; IMMUNOGLOBULINS; CYTOTOXIC T cells; COVID-19 vaccines
- Publication
Clinical Chemistry & Laboratory Medicine, 2023, Vol 61, Issue 9, pe172
- ISSN
1434-6621
- Publication type
Article
- DOI
10.1515/cclm-2023-0226