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- Title
Microfluidics-Based Organism Isolation from Whole Blood: An Emerging Tool for Bloodstream Infection Diagnosis.
- Authors
Burklund, Alison; Zhang, John X. J.
- Abstract
The diagnosis of bloodstream infections presents numerous challenges, in part, due to the low concentration of pathogens present in the peripheral bloodstream. As an alternative to existing time-consuming, culture-based diagnostic methods for organism identification, microfluidic devices have emerged as rapid, high-throughput and integrated platforms for bacterial and fungal enrichment, detection, and characterization. This focused review serves to highlight and compare the emerging microfluidic platforms designed for the isolation of sepsis-causing pathogens from blood and suggest important areas for future research.
- Subjects
MICROFLUIDIC devices; BLOOD; INFECTION; DIAGNOSIS; COMMUNICABLE diseases; NEONATAL sepsis
- Publication
Annals of Biomedical Engineering, 2019, Vol 47, Issue 7, p1657
- ISSN
0090-6964
- Publication type
Article
- DOI
10.1007/s10439-019-02256-7