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- Title
Doporučený postup k vedení antibiotické léčby komunitních a nozokomiálních bakteriálních pneumonií u pacientů s kritickým stupněm covid-19.
- Authors
DOUBRAVSKÁ, L.; SEDLÁKOVÁ, M. HTOUTOU; BOGDANOVÁ, K.; TUREK, R.; KLEMENTOVÁ, O.; KOLÁŘ, M.
- Abstract
Bacterial pneumonia in critically ill patients with COVID-19 poses a significant healthcare concern. The critical stage of COVID-19 encompasses patients experiencing acute respiratory failure, septic shock, and/or multiorgan failure. Data from the University Hospital Olomouc indicate that the incidence of bacterial community-acquired pneumonia (CAP) and hospital-acquired pneumonia (HAP) in critically ill patients with COVID-19 can reach 27% and 46%, respectively. These patients with bacterial CAP and HAP have higher mortality rates (38% and 56%, respectively) compared to critical COVID-19 patients without bacterial infection (11%). Given the severity of their condition, concerns regarding delayed initiation of antibiotic therapy are justified, as it could result in the development or progression of sepsis and increased mortality. On the other hand, unnecessary antibiotic treatment leads to adverse effects, dysbiosis, increased risk of secondary bacterial infections, development of antimicrobial resistance, and ultimately increased mortality. The present guidelines provide a comprehensive framework of strategies for the diagnosis and treatment of bacterial pneumonia in patients with critical COVID-19.
- Subjects
COVID-19; BACTERIAL diseases; ADULT respiratory distress syndrome; COMMUNITY-acquired pneumonia; MULTIPLE organ failure; SEPSIS; SEPTIC shock
- Publication
Klinická Mikrobiologie a Infekční Lékařství, 2023, Vol 29, Issue 4, p120
- ISSN
1211-264X
- Publication type
Article