We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Gas Permeation and Hemocompatibility of Novel Perfluorinated Polymers for Blood Oxygenation.
- Authors
Alentiev, A. Yu.; Belov, N. A.; Nikiforov, R. Yu.; Polunin, E. V.; Borovkova, N. V.; Evseev, A. K.; Makarov, M. S.; Goroncharovskaya, I. V.; Storozheva, M. V; Zhuravel, V. S.
- Abstract
Abstract: Gas permeation properties of three highly permeable perfluorinated polymers (polyhexafluoropropylene (PHFP), amorphous Teflon AF2400, and polyperfluoro(2-methyl-2-ethyl-dioxole-1,3) (PPFMED)), which are promising materials for the dense thin layer of hollow fiber membranes for extracorporeal membrane oxygenation have been studied using nitrogen, oxygen, and carbon dioxide. Hemocompatibility of the polymeric films has also been investigated on whole blood from healthy donors. Gas permeation of the polymers increases in the order PHFP < PPFMEDD < AF2400, with PHFP alone having the permeability coefficients of the gases do not below those of polydimethylsiloxane applied as the selective layer of blood oxygenation membranes. Hemocompatibility of the polymers declines in the order PHFP > PPFMED > AF2400, with the most permeable polymer AF2400 exhibiting the worst hemocompatibility among the other polymers studied. Polyperfluoro(2-methyl-2-ethyl-dioxole-1,3) is shown to be the most appropriate polymer to fabricate hollow fiber membranes for blood oxygenation.
- Subjects
POLYMERIC membranes; POLYMERIC composites; POLYMERS; OXYGENATION (Chemistry); PERMEABILITY; COEFFICIENTS (Statistics)
- Publication
Petroleum Chemistry, 2018, Vol 58, Issue 9, p740
- ISSN
0965-5441
- Publication type
Article
- DOI
10.1134/S0965544118090025