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- Title
Successful Treatment of Antibiotic-resistant, Poly-microbial Bone Infection With Bacteriophages and Antibiotics Combination.
- Authors
Nir-Paz, Ran; Gelman, Daniel; Khouri, Ayman; Sisson, Brittany M; Fackler, Joseph; Alkalay-Oren, Sivan; Khalifa, Leron; Rimon, Amit; Yerushalmy, Ortal; Bader, Reem; Amit, Sharon; Coppenhagen-Glazer, Shunit; Henry, Matthew; Quinones, Javier; Malagon, Francisco; Biswas, Biswajit; Moses, Allon E; Merril, Greg; Schooley, Robert T; Brownstein, Michael J
- Abstract
A patient with a trauma-related left tibial infection associated with extensively drug-resistant Acinetobacter baumannii and multidrug-resistant Klebsiella pneumoniae was treated with bacteriophages and antibiotics. There was rapid tissue healing and positive culture eradication. As a result, the patient's leg did not have to be amputated and he is undergoing rehabilitation.
- Subjects
ANTIBIOTICS; TREATMENT of bone diseases; BIOTHERAPY; BONE diseases; COMBINED modality therapy; DRUG resistance in microorganisms; TIBIA; TREATMENT effectiveness; DISEASE eradication
- Publication
Clinical Infectious Diseases, 2019, Vol 69, Issue 11, p2015
- ISSN
1058-4838
- Publication type
Article
- DOI
10.1093/cid/ciz222