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- Title
Delayed onset renal failure in a patient on tenofovir based antiretroviral regimen.
- Authors
Krishna, M. Murali; Subbalaxmi, M. V. S.; Uppin, Megha; Radhika, S.
- Abstract
Tenofovir is recommended as one of the first line agents in combination with other antiretroviral drugs for management of human immunodeficiency virus (HIV). It is known to cause renal failure after exposure for a median duration of 5 months. We report tenofovir induced adverse drug reaction in a 56-year-old female patient who was diagnosed to have HIV 1 infection since 10 years. The combination antiretroviral treatment included tenofovir, emtricitabine and ritonavir/lopinavir regimen since the last 6 years. She presented with recent onset renal failure and renal biopsy showed interstitial nephritis which could probably attributable to tenofovir.
- Subjects
TENOFOVIR; ANTIRETROVIRAL agents; HIV infections; THERAPEUTICS; RENAL biopsy; EMTRICITABINE
- Publication
Indian Journal of Pharmacology, 2014, Vol 46, Issue 2, p230
- ISSN
0253-7613
- Publication type
Article
- DOI
10.4103/0253-7613.129330