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- Title
Rifaximin may induce rifampicin resistance in coagulase‐negative staphylococci.
- Authors
Schulte, Lina M.; Nattermann, Jacob; Strassburg, Christian P.; Lutz, Philipp
- Abstract
Rifaximin is an oral, poorly absorbed antibiotic which is very effective in the prevention of hepatic encephalopathy (HE), a potentially severe complication of liver disease arising mainly in patients with advanced cirrhosis. However, in coagulase-negative staphylococci, 68% ( I n i = 13/19) were rifampicin resistant in patients taking rifaximin versus only 11% ( I n i = 3/28) in patients without rifaximin ( I p i < .001) (Figure 1C). Rifaximin may induce rifampicin resistance in coagulase-negative staphylococci.
- Subjects
RIFAXIMIN; STAPHYLOCOCCUS; URINARY tract infections; RIFAMPIN; PREGNANE X receptor; PROSTHETIC heart valves
- Publication
Liver International, 2023, Vol 43, Issue 9, p2039
- ISSN
1478-3223
- Publication type
Article
- DOI
10.1111/liv.15667