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- Title
HIV Infection among Low-Risk First Lifetime Testers in Rome, 1990-2000.
- Authors
Galati, V.; Serraino, D.; Puro, V.; Orchi, N.; De Carli, G.; Scognamiglio, P.; Nicastri, E.; Piselli, P.; Nurra, G.; Angeletti, C.; Girardi, E.; Ippolito, G.
- Abstract
Background: HIV spread among low-risk populations through heterosexual intercourse is a major public health concern. This study was aimed at describing prevalence and determinants of HIV infection among Italian low-risk subjects seeking their first lifetime HIV test. Patients and Methods: Information collected between January 1990 and December 2000 at a major counseling and testing site in Rome, Italy, was analyzed. Multiple logistic regression odds ratios (OR) and 95% confidence intervals (CI) were computed. Results: Among the 14,313 study subjects, 64 (0.4%) were seropositive for HIV infection. HIV seropositivity increased with age (OR = 4.0, 95% CI: 2.1-7.6 for ≥ 40 years vs 18-24), and it seemed to be more common among men (OR = 1.6, lower 95% CI:0.9). There was no evidence of temporal. variations, whereas motivations for HIV testing were strongly associated with HIV prevalence. Testing for alarming symptoms (OR = 13.8) or for heterosexual. intercourse (OR = 11.0) were associated with a more than 10-fold increased HIV risk. Conclusion: Our findings are consistent with data from other industrialized countries and they show a strong association between HIV seropositivity and reason for first-time testing. Moreover, they indicate a stable trend of HIV prevalence among low-risk persons in the last decade. Further studies on time trends in low-risk populations would be useful to evaluate current HIV prevention programs.
- Subjects
HIV infections; LENTIVIRUS diseases; HIV-positive persons; STATISTICAL hypothesis testing; PUBLIC health; HIV
- Publication
Infection, 2005, Vol 33, Issue 2, p61
- ISSN
0300-8126
- Publication type
Article
- DOI
10.1007/s15010-005-4040-5