We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Is mesh fixation necessary in abdominal hernia repair?
- Authors
Zieren, J.; Castenholz, Eric; Jacobi, Christoph A.; Zieren, Hans U.; Müller, Jochen M.
- Abstract
Background: Abdominal hernia repair with implantation of synthetic meshes using the sublay technique has resulted in low recurrence rates and high patient satisfaction. Aim: The purpose of this experimental animal study was to investigate whether mesh fixation is necessary in abdominal hernia repair using a polypropylene mesh in the sublay technique. Methods: Forty-five rats were divided into three groups after creating an abdominal wall defect ( CG control group, no mesh implantation; NoFixG mesh implantation without fixation group; SG mesh with suture fixation group) with 15 animals in each group. Endpoints were clinical herniation pressure, hydroxyproline (HP) concentration, mesh shape and number of fibroblasts/collagen fibres of the anchor zone 7, 14 and 90 days after implantation. Results: Herniation pressure, HP content and number of fibroblasts were similar between NoFixG and SG, although significantly higher in these groups than in the CG ( P<0.05). Both mesh groups had significantly higher counts of fibroblasts and collagen fibres than the CG. Mesh shrinking occurred in both groups but was less in the SG. Conclusion: Mesh fixation was not mandatory in abdominal hernia repair using this animal model.
- Publication
Langenbeck's Archives of Surgery, 1999, Vol 384, Issue 1, p71
- ISSN
1435-2443
- Publication type
Article
- DOI
10.1007/s004230050177