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- Title
Research on the immunosuppressive activity of ingredients contained in sunscreens.
- Authors
Frikeche, Jihane; Couteau, Céline; Roussakis, Christos; Coiffard, Laurence
- Abstract
The immunosuppressive properties of Benzophenone-4, an UV-filter and three ingredients, Allantoin, Bisabolol and Enoxolon used in sunscreen formulation, previously characterized as anti-inflammatory compounds, are studied. The results of this study demonstrate that four tested molecules have effects on DCs and T cells which are the most important cells of the immune system. The impact is also visible on keratinocyte cells which are in the direct contact with skin sunscreens. Each ingredient should be used with caution at reduced doses or even removed from some cosmetic preparations, such as sunscreens.
- Subjects
IMMUNOSUPPRESSION; SUNSCREENS (Cosmetics); COSMETICS additives; BENZOPHENONES; PHYSIOLOGICAL effects of ultraviolet radiation; ALLANTOIN; ANTI-inflammatory agents
- Publication
Archives of Dermatological Research, 2015, Vol 307, Issue 3, p211
- ISSN
0340-3696
- Publication type
Article
- DOI
10.1007/s00403-014-1528-9