We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Diffuse Metastasized Testicular Teratoma and Paraneoplastic Thyreotoxicosis.
- Authors
Derakhshani; Klotz; Heidenreich; Engelmann
- Abstract
Paraneoplastic syndromes are rare entities in patients with excessive HCG production. This has been attributed to the thyroid-stimulating hormone-like activity of HCG. In most cases hyperthyroidism remains subclinical. We report on a patient with diffuse metastasized malignant teratoma and thyreotoxicosis due to excessive levels of tumor-derived HCG. This complication of nonseminomatous germ cell tumors is associated with potential morbidity and the need for prompt recognition is stressed. Treatment consists of standard antithyroid medication and immediate cytoreductive chemotherapy to reduce the paraneoplastic stimulus. Evaluation of thyroid hormone levels in all patients with serum HCG levels exceeding 20,000 U/l is recommended.Copyright © 2000 S. Karger AG, Basel
- Subjects
METASTASIS; TERATOMA; PARANEOPLASTIC syndromes; TUMORS; HYPERTHYROIDISM
- Publication
Urologia Internationalis, 1999, Vol 63, Issue 4, p265
- ISSN
0042-1138
- Publication type
Article
- DOI
10.1159/000030466