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- Title
Reconstruction of mammalian oocytes by germinal vesicle transfer: A systematic review.
- Authors
Darbandi, Sara; Darbandi, Mahsa; Khorram Khorshid, Hamid Reza; Shirazi, Abolfazl; Sadeghi, Mohammad Reza; Agarwal, Ashok; Al-Hasani, Safaa; Naderi, Mohammad Mehdi; Ayaz, Ahmet; Akhondi, Mohammad Mehdi
- Abstract
Nuclear transfer procedures have been recently applied for clinical and research targets as a novel assisted reproductive technique and were used for increasing the oocyte activity during its growth and maturation. In this review, we summarized the nuclear transfer technique for germinal vesicle stage oocytes to reconstruct the maturation of them. Our study covered publications between 1966 and August 2017. In result utilized germinal vesicle transfer techniques, fusion, and fertilization survival rate on five different mammalian species are discussed, regarding their potential clinical application. It seems that with a study on this method, there is real hope for effective treatments of old oocytes or oocytes containing mitochondrial problems in the near future.
- Subjects
TRANSPLANTATION of cell nuclei; OVUM; REPRODUCTION; MITOCHONDRIA; GERMINAL vesicles
- Publication
International Journal of Reproductive Biomedicine, 2017, Vol 15, Issue 10, p601
- ISSN
2476-4108
- Publication type
Article