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- Title
Impact of comorbid alcohol use disorder on healthrelated quality of life among clinically depressed patients.
- Authors
Luoto, K.; Koivukangas, A.; Lassila, A.; Sintonen, H.; Leinonen, E.; Kampman, O.
- Abstract
Introduction: Depression and alcohol use disorders (AUD) have a negative impact on health-related quality of life (HRQOL) in general population. However, research on the association of comorbid AUD and HRQOL among clinically depressed patients is scarce. Objectives: The aim of this study was to explore the change in HRQOL among specialized mental health care depressive patients who typically have various concurrent psychiatric disorders. The focus was in the impact of comorbid AUD on improvement of HRQOL in this sample. Methods: The study population (n=242) scored at least 17 points in Beck Depression Inventory at baseline and did not suffer from psychotic disorders. Those with baseline Alcohol Use Disorders Identification Test (AUDIT) > 10 were categorized as AUD group (n=99, 40.9%). Treatment intervention comprised behavioural activation for all and additional motivational interviewing for those with AUD. HRQOL was assessed regularly during 24-months follow-up by 15D questionnaire. AUD and non-AUDpatients were compared and the factors explaining 15Dscore were analyzed. Results: 15D score improved in the whole study population during the first year of follow-up (improvement 0 - 6 months, p<0.001; 6 - 12 months, p=0.001). A difference between AUD groups was found only at 24-months follow-up point when mean 15D score in non-AUD group was better (p=0.002). In linear mixed model for 15D the changes were better explained with other factors than comorbid AUD. Conclusions: The treatment intervention was successful in terms of improvement in HRQOL regardless of the comorbid AUD.
- Subjects
ALCOHOLISM; MENTAL health services; DEPRESSED persons; MOTIVATIONAL interviewing; COGNITIVE therapy; COMORBIDITY
- Publication
European Psychiatry, 2020, Vol 63, pS371
- ISSN
0924-9338
- Publication type
Article