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- Title
Babesia microti Variant With Multiple Resistance Mutations Detected in an Immunocompromised Patient Receiving Atovaquone Prophylaxis.
- Authors
Holbrook, Nolan R; Klontz, Erik H; Adams, Gordon C; Schnittman, Samuel R; Issa, Nicolas C; Bond, Sheila A; Branda, John A; Lemieux, Jacob E
- Abstract
We report Babesia microti genomic sequences with multiple mutations in the atovaquone-target region of cytochrome b, including a newly identified Y272S mutation, plus 1 mutation of undetermined significance in the azithromycin-associated ribosomal protein L4. The parasite was sequenced from an immunocompromised patient on prophylactic atovaquone for Pneumocystis pneumonia before diagnosis of babesiosis.
- Publication
Open Forum Infectious Diseases, 2023, Vol 10, Issue 3, p1
- ISSN
2328-8957
- Publication type
Article
- DOI
10.1093/ofid/ofad097