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- Title
Inflammatory Markers During Early Treatment of Seroconverters in a Randomized Placebo-Controlled Trial of PrEP (ANRS-IPERGAY).
- Authors
Chawki, Sylvain; Charreau, Isabelle; Gabassi, Audrey; Carette, Diane; Cua, Eric; Cotte, Laurent; Pialoux, Gilles; Pintado, Claire; Meyer, Laurence; Chaix, Marie-Laure; Delaugerre, Constance; Molina, Jean-Michel
- Abstract
HIV-related inflammation is associated with poor outcomes. We describe inflammatory biomarkers in 17 participants in a pre-exposure prophylaxis trial who seroconverted with very early initiation of antiretroviral therapy. Inflammation peaked at the time of HIV infection and returned to baseline within 6–12 months. Starting antiretroviral therapy very early could help mitigate long-lasting HIV-related inflammation.
- Publication
Open Forum Infectious Diseases, 2021, Vol 8, Issue 3, p1
- ISSN
2328-8957
- Publication type
Article
- DOI
10.1093/ofid/ofab085