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- Title
X-ray structure of cyanide-bound bovine heart cytochrome c oxidase in the fully oxidized state at 2.0 Å resolution.
- Authors
Yano, Naomine; Muramoto, Kazumasa; Mochizuki, Masao; Shinzawa-Itoh, Kyoko; Yamashita, Eiki; Yoshikawa, Shinya; Tsukihara, Tomitake
- Abstract
The X-ray structure of cyanide-bound bovine heart cytochrome c oxidase in the fully oxidized state was determined at 2.0 Å resolution. The structure reveals that the peroxide that bridges the two metals in the fully oxidized state is replaced by a cyanide ion bound in a nearly symmetric end-on fashion without significantly changing the protein conformation outside the two metal sites.
- Subjects
CYANIDES; CYTOCHROME c; OXIDASES; PEROXIDES; IONS
- Publication
Acta Crystallographica: Section F, Structural Biology Communications, 2015, Vol 71, Issue 6, p726
- ISSN
2053-230X
- Publication type
Article
- DOI
10.1107/S2053230X15007025