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- Title
Rapid Remission of Sunburn-Induced Guttate Psoriasis with Guselkumab.
- Authors
Bartholomew, Erin; Chung, Bo-Young; Davis, Mitchell; Yeroushalmi, Samuel; Chung, Mimi; Hakimi, Marwa; Bhutani, Tina; Liao, Wilson
- Abstract
Guselkumab is an anti-interleukin-23 monoclonal antibody that is approved for plaque psoriasis and psoriatic arthritis. We present a case of a 28-year-old female patient with acute onset of guttate psoriasis after a blistering sunburn. She had no personal or family history of psoriasis or chronic inflammatory skin disease. The guttate psoriasis was refractory to topical treatment. After the first dose of guselkumab (100 mg subcutaneous injection), the patient experienced near-clearance of her guttate psoriasis, with continued improvement and drug-free remission 8 months after cessation of treatment. Dermatologists could consider guselkumab as a treatment option for patients with guttate psoriasis. Future studies should examine the potential for guselkumab to induce drug-free remissions in guttate psoriasis.
- Subjects
PSORIASIS; PSORIATIC arthritis; SUBCUTANEOUS injections; SKIN diseases; MONOCLONAL antibodies; SUNBURN
- Publication
Dermatology & Therapy, 2023, Vol 13, Issue 10, p2473
- ISSN
2193-8210
- Publication type
Case Study
- DOI
10.1007/s13555-023-01013-y