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- Title
Thymocytes are activated by toluene inhalation through the transcription factors NF-κB, STAT5 and NF-AT.
- Authors
Jiqin Liu; Yoshida, Yasuhiro; Kunugita, Naoki; Noguchi, Junko; Sugiura, Tsutomu; Ning Ding; Arashidani, Keiichi; Fujimaki, Hidekazu; Yamashita, Uki
- Abstract
The article explores the influence of toluene's low-level inhalation in naive immune cells of mice. It examines the effect of toluene on the central nervous system as well as its effect in the cellular and molecular levels. It also discusses the neurotoxic effects of toluene which have been reported on several studies on naive immune cells.
- Subjects
TOLUENE; TRANSCRIPTION factors; CELLS; LABORATORY mice; CENTRAL nervous system
- Publication
Journal of Applied Toxicology, 2010, Vol 30, Issue 7, p656
- ISSN
0260-437X
- Publication type
Article
- DOI
10.1002/jat.1536