We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Influence of the Glassy Fraction Surface of a ZrCoAlAg Ribbon Alloy on the Bioactive Response to Simulated Body Fluid and Its Effect on Cell Viability.
- Authors
Escamilla, Aish; Verduzco, Jorge; Núñez, Rosa; Figueroa, Ignacio; García, René
- Abstract
To purpose of this work is to determine the biocompatibility of the Zr58Co21Al9Ag12 alloy; vitreous ribbons of the Zr58Co21Al9Ag12 alloy were obtained by a chill block melt spinner. They were characterized by X-ray diffraction and transmission electron microscopy. Chemical homogeneity was examined by scanning electron microscopy. Similarly, thermal analysis was performed using differential scanning calorimetry. The nanoindentation test was performed with a Berkovich nanoindenter. Subsequently, the bioactivity was evaluated by chemical immersion in simulated body fluid. After immersion, it was characterized by XRD. A cell adhesion test was performed using mesenchymal stem cells from human dental pulp. Cell viability and proliferation were evaluated with a CCK-8 assay using human lymphocytes. The ribbons have crystalline phases close to 20%. The thermal parameters, Young's modulus, and hardness were obtained. After the immersion test, Ca and P were identified. Ion release does not exceed critical levels for human cells. The alloy has a higher concentration of adhered cells compared to Ti6Al4V. The alloy remains bio-inert with respect to apatite formation; however, it exhibits excellent cell viability, proliferation, and adhesion behavior.
- Subjects
BODY fluids; REGULATION of body fluids; MESENCHYMAL stem cells; ALLOYS; DIFFERENTIAL scanning calorimetry; HUMAN stem cells; CELL survival
- Publication
Metals (2075-4701), 2023, Vol 13, Issue 1, p55
- ISSN
2075-4701
- Publication type
Article
- DOI
10.3390/met13010055