Found: 35
Select item for more details and to access through your institution.
ATF4 induction through an atypical integrated stress response to ONC201 triggers p53-independent apoptosis in hematological malignancies.
- Published in:
- Science Signaling, 2016, v. 9, n. 415, p. 1, doi. 10.1126/scisignal.aac4380
- By:
- Publication type:
- Article
Abrogation of nuclear receptors Nr4a3 andNr4a1 leads to development of acute myeloid leukemia.
- Published in:
- Nature Medicine, 2007, v. 13, n. 6, p. 730, doi. 10.1038/nm1579
- By:
- Publication type:
- Article
Apoptosis repressor with caspase recruitment domain modulates second mitochondrial-derived activator of caspases mimetic-induced cell death through BIRC2/ MAP3K14 signalling in acute myeloid leukaemia.
- Published in:
- British Journal of Haematology, 2014, v. 167, n. 3, p. 376, doi. 10.1111/bjh.13054
- By:
- Publication type:
- Article
Role for PKC δ in Fenretinide-Mediated Apoptosis in Lymphoid Leukemia Cells.
- Published in:
- Journal of Signal Transduction, 2010, p. 1, doi. 10.1155/2010/584657
- By:
- Publication type:
- Article
MDM2 Inhibitor, Nutlin 3a, Induces p53 Dependent Autophagy in Acute Leukemia by AMP Kinase Activation.
- Published in:
- PLoS ONE, 2015, v. 10, n. 10, p. 1, doi. 10.1371/journal.pone.0139254
- By:
- Publication type:
- Article
Mitochondrial Profiling of Acute Myeloid Leukemia in the Assessment of Response to Apoptosis Modulating Drugs.
- Published in:
- PLoS ONE, 2015, v. 10, n. 9, p. 1, doi. 10.1371/journal.pone.0138377
- By:
- Publication type:
- Article
Concomitant inhibition of DNA methyltransferase and BCL-2 protein function synergistically induce mitochondrial apoptosis in acute myelogenous leukemia cells.
- Published in:
- Annals of Hematology, 2012, v. 91, n. 12, p. 1861, doi. 10.1007/s00277-012-1537-8
- By:
- Publication type:
- Article
Chromatin Profiles Are Prognostic of Clinical Response to Bortezomib-Containing Chemotherapy in Pediatric Acute Myeloid Leukemia: Results from the COG AAML1031 Trial.
- Published in:
- Cancers, 2024, v. 16, n. 8, p. 1448, doi. 10.3390/cancers16081448
- By:
- Publication type:
- Article
Bone marrow stromal cells induce an ALDH<sup>+</sup> stem cell-like phenotype and enhance therapy resistance in AML through a TGF-β-p38-ALDH2 pathway.
- Published in:
- PLoS ONE, 2020, v. 15, n. 11, p. 1, doi. 10.1371/journal.pone.0242809
- By:
- Publication type:
- Article
BETP degradation simultaneously targets acute myelogenous leukemia stem cells and the microenvironment.
- Published in:
- 2019
- By:
- Publication type:
- journal article
Targeting PKC-mediated signal transduction pathways using enzastaurin to promote apoptosis in acute myeloid leukemia-derived cell lines and blast cells.
- Published in:
- Journal of Cellular Biochemistry, 2011, v. 112, n. 6, p. 1696, doi. 10.1002/jcb.23090
- By:
- Publication type:
- Article
AML-284: Emvododstat (PTC299) Targets De Novo Pyrimidine Synthesis in Acute Myeloid Leukemia.
- Published in:
- Clinical Lymphoma, Myeloma & Leukemia, 2021, v. 21, p. S300, doi. 10.1016/S2152-2650(21)01714-6
- By:
- Publication type:
- Article
Poster: AML-284: Emvododstat (PTC299) Targets De Novo Pyrimidine Synthesis in Acute Myeloid Leukemia.
- Published in:
- Clinical Lymphoma, Myeloma & Leukemia, 2021, v. 21, p. S215, doi. 10.1016/S2152-2650(21)01356-2
- By:
- Publication type:
- Article
Synergistic Activity of the MCL-1 Inhibitor S63845 with Midostaurin in Preclinical Human Models of FLT3-ITD Mutated Acute Myeloid Leukemia (AML).
- Published in:
- Clinical Lymphoma, Myeloma & Leukemia, 2019, v. 19, p. S220, doi. 10.1016/j.clml.2019.07.095
- By:
- Publication type:
- Article
Dual Inhibition of MDM2 and XPO1 Induces Synergistic Apoptosis in Wild-type p53 Acute Myeloid Leukemia Through Nuclear Accumulation of p53 and Suppression of c-Myc.
- Published in:
- Clinical Lymphoma, Myeloma & Leukemia, 2019, v. 19, p. S215, doi. 10.1016/j.clml.2019.07.085
- By:
- Publication type:
- Article
Targeting NOTCH1-MYC-CD44 Axis to Eliminate Leukemia Initiating Cells (LIC) in T-ALL.
- Published in:
- Clinical Lymphoma, Myeloma & Leukemia, 2019, v. 19, p. S196, doi. 10.1016/j.clml.2019.07.046
- By:
- Publication type:
- Article
MCL-1 Up-Regulation through MAPK Activation Confers Acquired Resistance to BCL-2 Inhibitor ABT-199 in Pre-Clinical AML Models.
- Published in:
- Clinical Lymphoma, Myeloma & Leukemia, 2017, v. 17, p. S2, doi. 10.1016/j.clml.2017.09.025
- By:
- Publication type:
- Article
Upregulation of MCL-1 through MAPK Activation Maintaining Mitochondrial Oxidative Phosphorylation Confers Acquired Resistance to BCL-2 Inhibitor Venetoclax in AML.
- Published in:
- Clinical Lymphoma, Myeloma & Leukemia, 2017, v. 17, p. S285, doi. 10.1016/j.clml.2017.07.069
- By:
- Publication type:
- Article
Targeting MAPK Signaling Pathway with Cobimetinib (GDC-0973) Enhances Anti-Leukemia Efficacy of Venetoclax (ABT-199/GDC-0199) in Acute Myeloid Leukemia Models.
- Published in:
- Clinical Lymphoma, Myeloma & Leukemia, 2017, v. 17, p. S282, doi. 10.1016/j.clml.2017.07.064
- By:
- Publication type:
- Article
PML-RARα and AML1–ETO translocations are rarely associated with methylation of the RARβ2 promoter.
- Published in:
- Annals of Hematology, 2006, v. 85, n. 10, p. 689, doi. 10.1007/s00277-006-0148-7
- By:
- Publication type:
- Article
Correction: Combined inhibition of BCL-2 and MCL-1 overcomes BAX deficiency-mediated resistance of TP53-mutant acute myeloid leukemia to individual BH3 mimetics.
- Published in:
- 2023
- By:
- Publication type:
- Correction Notice
Combined inhibition of BCL-2 and MCL-1 overcomes BAX deficiency-mediated resistance of TP53-mutant acute myeloid leukemia to individual BH3 mimetics.
- Published in:
- Blood Cancer Journal, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41408-023-00830-w
- By:
- Publication type:
- Article
Correction: Combined inhibition of BCL-2 and MCL-1 overcomes BAX deficiency-mediated resistance of TP53-mutant acute myeloid leukemia to individual BH3 mimetics.
- Published in:
- 2023
- By:
- Publication type:
- Correction Notice
Combined inhibition of BCL-2 and MCL-1 overcomes BAX deficiency-mediated resistance of TP53-mutant acute myeloid leukemia to individual BH3 mimetics.
- Published in:
- Blood Cancer Journal, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41408-023-00830-w
- By:
- Publication type:
- Article
The Tc2 Transposon of Caenorhabditis elegans Has the Structure of a Self-Regulated Element.
- Published in:
- DNA & Cell Biology, 1992, v. 11, n. 2, p. 111, doi. 10.1089/dna.1992.11.111
- By:
- Publication type:
- Article
Genetic biomarkers of sensitivity and resistance to venetoclax monotherapy in patients with relapsed acute myeloid leukemia.
- Published in:
- American Journal of Hematology, 2018, v. 93, n. 8, p. E202, doi. 10.1002/ajh.25146
- By:
- Publication type:
- Article
Decreased sensitivity of 17p-deleted chronic lymphocytic leukemia cells to a small molecule BCL-2 antagonist ABT-737.
- Published in:
- Cancer (0008543X), 2012, v. 118, n. 4, p. 1023, doi. 10.1002/cncr.26360
- By:
- Publication type:
- Article
High incidence of IDH mutations in acute myeloid leukaemia with cuplike nuclei.
- Published in:
- British Journal of Haematology, 2011, v. 155, n. 1, p. 125, doi. 10.1111/j.1365-2141.2011.08646.x
- By:
- Publication type:
- Article
PI3K inhibitor GDC-0941 enhances apoptotic effects of BH-3 mimetic ABT-737 in AML cells in the hypoxic bone marrow microenvironment.
- Published in:
- Journal of Molecular Medicine, 2013, v. 91, n. 12, p. 1383, doi. 10.1007/s00109-013-1076-3
- By:
- Publication type:
- Article
Inhibition of FAO in AML co-cultured with BM adipocytes: mechanisms of survival and chemosensitization to cytarabine.
- Published in:
- Scientific Reports, 2018, v. 8, n. 1, p. 1, doi. 10.1038/s41598-018-35198-6
- By:
- Publication type:
- Article
Induction of p53-mediated transcription and apoptosis by exportin-1 ( XPO1) inhibition in mantle cell lymphoma.
- Published in:
- Cancer Science, 2014, v. 105, n. 7, p. 795, doi. 10.1111/cas.12430
- By:
- Publication type:
- Article
Correction: Activation of RAS/MAPK pathway confers MCL-1 mediated acquired resistance to BCL-2 inhibitor venetoclax in acute myeloid leukemia.
- Published in:
- 2022
- By:
- Publication type:
- Correction Notice
Activation of RAS/MAPK pathway confers MCL-1 mediated acquired resistance to BCL-2 inhibitor venetoclax in acute myeloid leukemia.
- Published in:
- Signal Transduction & Targeted Therapy, 2022, v. 7, n. 1, p. 1, doi. 10.1038/s41392-021-00870-3
- By:
- Publication type:
- Article
Activation of RAS/MAPK pathway confers MCL-1 mediated acquired resistance to BCL-2 inhibitor venetoclax in acute myeloid leukemia.
- Published in:
- Signal Transduction & Targeted Therapy, 2022, v. 7, n. 1, p. 1, doi. 10.1038/s41392-021-00870-3
- By:
- Publication type:
- Article
Activation of RAS/MAPK pathway confers MCL-1 mediated acquired resistance to BCL-2 inhibitor venetoclax in acute myeloid leukemia.
- Published in:
- Signal Transduction & Targeted Therapy, 2022, v. 7, n. 1, p. 1, doi. 10.1038/s41392-021-00870-3
- By:
- Publication type:
- Article