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- Title
The Many Faces of Solitary and Multiple Erythema Migrans.
- Authors
ERIKSSON, Pernilla; SCHRÖDER, Marika T.; NIIRANEN, Kirsi; NEVANLINNA, Antti; PANELIUS, Jaana; RANKI, Annamari
- Abstract
Case definitions for European Lyme disease have been published. However, multiple erythema migrans may pose a diagnostic challenge. Therefore, we retrospectively reviewed the clinical and serological findings and response to therapy in a cohort of consecutive 54 patients with PCR-confirmed erythema migrans, referred to a university dermatology clinic. The proportion of patients with multiple erythema migrans lesions (usually 2 or 3) was almost equal (46%) to the proportion of patients with single erythema migrans lesions (54%). All patients, except for 2 multiple erythema migrans patients with a concomitant autoimmune disease, completely responded to treatment. In conclusion, multiple erythema migrans may be more common than anticipated, and since only 50% of the patients were seropositive when seeking medical help, PCR testing of skin lesions is helpful to confirm the diagnosis in clinically atypical cases.
- Subjects
LYME disease; RELAPSING fever; ERYTHEMA; CUTANEOUS manifestations of general diseases; SEROLOGY; DERMATOLOGY
- Publication
Acta Dermato-Venereologica, 2013, Vol 93, Issue 6, p693
- ISSN
0001-5555
- Publication type
Article
- DOI
10.2340/00015555-1549