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- Title
Haemodynamic and functional consequences of the iatrogenic atrial septal defect following Mitraclip therapy.
- Authors
Hart, E.; Zwart, K.; Teske, A.; Voskuil, M.; Stella, P.; Chamuleau, S.; Kraaijeveld, A.
- Abstract
Percutaneous MitraClip placement for treatment of severe mitral regurgitation in high surgical risk patients is a commonly performed procedure and requires a transseptal puncture to reach the left atrium. The resulting iatrogenic atrial septal defect (iASD) is not routinely closed, yet the haemodynamic and functional consequences of a persisting defect are not fully understood. Despite positive effects such as acute left atrial pressure relief, persisting iASDs are associated with negative consequences, namely significant bidirectional shunting and subsequent worse clinical outcome. Percutaneous closure of the iASD may therefore be desirable in selected cases. In this review we discuss the available literature on this matter.
- Subjects
MITRAL valve surgery; ATRIAL septal defect treatment; PERCUTANEOUS coronary intervention; MITRAL valve insufficiency; HEMODYNAMICS; HEALTH outcome assessment; THERAPEUTICS
- Publication
Netherlands Heart Journal, 2017, Vol 25, Issue 2, p137
- ISSN
1568-5888
- Publication type
Article
- DOI
10.1007/s12471-016-0928-1