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- Title
Management of oral cancer in Latin America.
- Authors
Costa Diaz, Otávio; Zanella, Virgilio; Janoski de Menezes, Juliana; Lim, Fiona; Wan, Bo Angela; Silva, Maurício F.
- Abstract
In Brazil, oral cavity cancer is the seventh most frequent cancer. Smoke and alcohol abuse are the major risk factors and squamous cell carcinoma accounts for 90% of the cases. The last edition of AJCC staging system had incorporated depth of invasion as a major prognostic factor and some changes in the nodal classification as well. Surgery is the mainstay of the treatment, and chemotherapy and radiation therapy are important in locally advanced tumors. Early stage tumors have good outcomes after surgery, intermediate risk tumors need adjuvant radiation therapy and high-risk disease need adjuvant chemoradiation. Irresectable tumors are treated with concomitant radiation therapy and chemotherapy. Induction chemotherapy failed to show a statistically significant increment in overall survival and increases treatment costs over concomitant chemoradiation. The treatment of oral cavity squamous cell carcinoma is challenging, and multidisciplinary approach is crucial.
- Subjects
LATIN America; CANCER chemotherapy; MEDICAL care costs; MOUTH tumors; RADIOTHERAPY; SQUAMOUS cell carcinoma; TUMOR classification; DISEASE risk factors
- Publication
Journal of Pain Management, 2019, Vol 12, Issue 3, p205
- ISSN
1939-5914
- Publication type
Article