We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
One simple and stable coating of mixed-charge copolymers on poly(vinyl chloride) films to improve antifouling efficiency.
- Authors
Zhang, Ling; Tang, Minjie; Zhang, Jinwei; Zhang, Pengsheng; Zhang, Jianhua; Deng, Liandong; Lin, Cunguo; Dong, Anjie
- Abstract
ABSTRACT An antifouling surface is highly desirable for many biomedical applications. In this study, poly(vinyl chloride) (PVC) films were endowed with the improved properties of resisting nonspecific protein adsorption and platelet adhesion simply through being coated with a kind of mixed-charge zwitterionic polymer, poly(3-sulfopropyl methacrylate-methacrylatoethyl trimethyl ammonium chloride-glycidyl methacrylate) (PSTG), with random moieties of negatively charged 3-sulfopropyl methacrylate potassium, positively charged [2-(methacryloyloxy)-ethyl] trimethylammonium chloride, and glycidyl methacrylate. The PSTG-grafted PVC films were formed by the simple immersion of an amino-functionalized PVC film into a PSTG solution. A grafting density of 220.84 µg/cm2 of PSTG4-grafted PVC film was successfully obtained. The PSTG4-grafted PVC film showed a lower contact angle (37.5 °) than the ungrafted PVC film (98.3 °). The in vitro protein adsorption results show that the bovine serum albumin adsorption amount decreased 6.72 µg/cm2 in the case of the PSTG4-grafted PVC film, whereas that on the ungrafted PVC film was 28.54 µg/cm2. So, PSTG-grafted PVC films could be promising materials for medical devices. © 2016 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2017, 134, 44632.
- Subjects
POLYVINYL chloride; COPOLYMERS; MEDICAL equipment; HEPARIN; POLYZWITTERIONS
- Publication
Journal of Applied Polymer Science, 2017, Vol 134, Issue 12, pn/a
- ISSN
0021-8995
- Publication type
Article
- DOI
10.1002/app.44632