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- Title
The physiology of venoarterial extracorporeal membrane oxygenation - A comprehensive clinical perspective.
- Authors
Fresiello, Libera; Hermens, Jeannine A. J.; Pladet, Lara; Meuwese, Christiaan L.; Donker, Dirk W.
- Abstract
Venoarterial extracorporeal membrane oxygenation (VA ECMO) has become a standard of care for severe cardiogenic shock, refractory cardiac arrest and related impending multiorgan failure. The widespread clinical use of this complex temporary circulatory support modality is still contrasted by a lack of formal scientific evidence in the current literature. This might at least in part be attributable to VA ECMO related complications, which may significantly impact on clinical outcome. In order to limit adverse effects of VA ECMO as much as possible an indepth understanding of the complex physiology during extracorporeally supported cardiogenic shock states is critically important. This review covers all relevant physiological aspects of VA ECMO interacting with the human body in detail. This, to provide a solid basis for health care professionals involved in the daily management of patients supported with VA ECMO and suffering from cardiogenic shock or cardiac arrest and impending multiorgan failure for the best possible care.
- Subjects
CARDIOGENIC shock; LEFT heart ventricle; CARDIOPULMONARY system physiology; EXTRACORPOREAL membrane oxygenation; MULTIPLE organ failure; HEMODYNAMICS; CARDIOPULMONARY bypass; BLOOD volume determination; BLOOD substitutes; PATIENT-centered care; CARDIAC output; CARDIAC arrest; ECHOCARDIOGRAPHY
- Publication
Perfusion, 2024, Vol 39, p5S
- ISSN
0267-6591
- Publication type
Article
- DOI
10.1177/02676591241237639