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- Title
Relapse of Intravenous Drug Use Triggered by Enfuvirtide, a Parenteral Antiretroviral Medication.
- Authors
Avelino-Silva, Vivian Iida; Li, Ho Yeh; Novaes, Christina Terra Gallafrio
- Abstract
Fuzeon® (enfuvirtide; Hoffmann-LaRoche, Nutley, NJ) is a parenteral medication prescribed to antiretroviral-experienced HIV patients. Clinicians are frequently concerned when prescribing enfuvirtide to former drug addicts because of the risk of triggering relapse, however, no previous report has described this adverse event. We describe two HIV-infected patients, previously abstinent from injection drug use, who experienced relapse or near-relapse situations after starting treatment with enfuvirtide. Along with the concerns related to adherence and to injection site reactions, clinicians who prescribe enfuvirtide should consider and discuss the risk of triggering relapse among former or recovering drug addicts.
- Subjects
SUBCUTANEOUS injections; HIV infections; SUBSTANCE abuse; DISEASE relapse; ENFUVIRTIDE (Drug)
- Publication
AIDS Patient Care & STDs, 2012, Vol 26, Issue 2, p71
- ISSN
1087-2914
- Publication type
Article
- DOI
10.1089/apc.2011.0343