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- Title
A new RHD variant allele (RHD Gly339Val) shows weakened D expression compared to RHD Gly339Glu and Gly339Arg mutants.
- Authors
Chun, Sejong; Lee, Ho‐Jin; Cho, Duck; Lee, Ho-Jin
- Abstract
We report a new I RHD i variant allele ( I RHD i 1016G>T, Gly339Val, GenBank Accession No. MF737523, ISBT nomenclature I RHD*DEL49 i .) We have performed epitope mapping of the D antigen and analyzed the expected effect of this variation with comparison to two other D weak-expressing variants with an amino acid change in the same position.
- Subjects
ALLELES; AMINO acid sequence; RESEARCH; GENETIC mutation; RESEARCH methodology; MEDICAL cooperation; EVALUATION research; COMPARATIVE studies; RH factor; GENES; AMINO acids
- Publication
Transfusion, 2020, Vol 60, Issue 7, pE17
- ISSN
0041-1132
- Publication type
journal article
- DOI
10.1111/trf.15908