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- Title
Defining epigenetic states through chromatin and RNA.
- Authors
Schübeler, Dirk; Elgin, Sarah C. R.
- Abstract
The article presents information on epigenetic states. The term epigenetics is used to describe heritable changes in genome function that occur without a change in DNA sequence. As such, epigenetics lies at the heart of the cellular memory crucial for development and provides an important avenue for sustained response to environmental stimuli. Nucleosomal histones are the target of a variety of post-translational modifications, including acetylation, phosphorylation, ubiquitination and methylation.
- Subjects
EPIGENESIS; NUCLEOTIDE sequence; GENETICS; GENOMES; DNA; HISTONES
- Publication
Nature Genetics, 2005, Vol 37, Issue 9, p917
- ISSN
1061-4036
- Publication type
Report
- DOI
10.1038/ng0905-917