We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Positron emission tomography-computed tomography surveillance for the node-positive neck after chemoradiotherapy.
- Authors
Rabalais, Amy G.; Walvekar, Rohan; Nuss, Daniel; McWhorter, Andrew; Wood, Charles; Fields, Robert; Mercante, Donald E.; Pou, Anna M.
- Abstract
Objectives/Hypothesis: To review our results with positron emission tomography and computed tomography fusion imaging (PET-CT) surveillance of the postchemoradiotherapy neck in patients with advanced head and neck squamous cell carcinoma. Study Design: Retrospective. Methods: Four hundred twenty-eight patients with advanced head and neck squamous cell carcinoma were treated with nonsurgical therapy from September 2002 to March 2007 and followed with post-treatment PET-CT surveillance of the neck. Fifty-two patients meeting inclusion criteria were analyzed. Sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and accuracy of PET-CT were determined. Results: Ten patients had a positive post-treatment PET-CT for residual neck disease, and 42 patients had negative scans. The NPV and PPV were 100% and 40%, respectively. The sensitivity, specificity, and accuracy were 100%, 87.5%, and 88%, respectively. Conclusions: Planned neck dissection can be deferred with a negative post-treatment PET-CT. Assuming a complete response at the primary site and a negative PET-CT scan, there may be a role for serial PET-CT surveillance in patients with residual palpable cervical lymphadenopathy. Laryngoscope, 2009
- Publication
Laryngoscope, 2009, Vol 119, Issue 6, p1120
- ISSN
0023-852X
- Publication type
Article
- DOI
10.1002/lary.20201