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- Title
Catalytic Enantioselective Isocyanide‐Based Reactions: Beyond Passerini and Ugi Multicomponent Reactions.
- Authors
Luo, Jian; Chen, Guo‐Shu; Chen, Shu‐Jie; Li, Zhao‐Dong; Liu, Yun‐Lin
- Abstract
The development of catalytic enantioselective isocyanide‐based reactions is currently of great interest because the resulting products are valuable in organic synthesis, pharmacological chemistry, and materials science. This review assembles and comprehensively summarizes the recent achievements in this rapidly growing area according to the reaction types. Special attention is paid to the advantages, limitations, possible mechanisms, and synthetic applications of each reaction. In addition, a personal outlook on the opportunities for further exploration is given at the end.
- Subjects
ORGANIC synthesis; MATERIALS science; RING formation (Chemistry)
- Publication
Chemistry - A European Journal, 2021, Vol 27, Issue 22, p6598
- ISSN
0947-6539
- Publication type
Article
- DOI
10.1002/chem.202003224