We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Possible Cardioprotective Effects of Lactate Infusion After Cardiac Arrest or Prolonged Myocardial Ischemia.
- Authors
Koyama, Takashi
- Abstract
This document discusses the potential cardioprotective effects of lactate infusion after cardiac arrest or prolonged myocardial ischemia. Experimental studies have shown that sodium lactate infusion can improve cardiovascular function, such as mean arterial pressure, cardiac output, and left ventricle surface shortening fraction, in animal models. Additionally, lactate administration during cardiopulmonary resuscitation has been found to reduce vasopressor requirements and the release of brain and cardiac injury biomarkers in swine. These findings suggest that lactate infusion may attenuate ischemia/reperfusion injury and have cardioprotective effects. Further research is needed to explore the potential benefits of lactate infusion in patients with cardiac arrest or myocardial ischemia.
- Subjects
MYOCARDIAL ischemia; CARDIAC arrest; LACTATES; LACTATION; ST elevation myocardial infarction
- Publication
Cardiovascular Drugs & Therapy, 2024, Vol 38, Issue 3, p417
- ISSN
0920-3206
- Publication type
Article
- DOI
10.1007/s10557-023-07524-2