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- Title
THE RELATIVE ANTIBACTERIAL EFFICIENCY OF IgM, IgG AND IgA FROM PIG COLOSTRUM.
- Authors
Knop, J.; Breu, H.; Wernet, P.; Rowley, D.
- Abstract
The article presents a study related to the antibacterial efficiency of various immunoglobulins (IgM, IgG and IgA) isolated from pig colostrum and infected with Escherichia coli. It seems likely that the IgA class of immunoglobulin represents the major component of copro-antibodies. The haemagglutinating activity was high in the IgM and low in the IgA and IgG fractions, and IgA showed little activity in the bactericidal test involving complement, but in terms of its opsonising ability it was much more effective than either IgM or IgG. IgA does not fix or activate complement, so a direct antibacterial action with complement against gram negative bacteria seems unlikely.
- Subjects
IMMUNOGLOBULINS; COLOSTRUM; ESCHERICHIA coli; ANTIBACTERIAL agents; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M
- Publication
Australian Journal of Experimental Biology & Medical Science, 1971, Vol 49, Issue 4, p405
- ISSN
0004-945X
- Publication type
Article
- DOI
10.1038/icb.1971.42