We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
超声造影参数联合血清 AFP、DKK1 在原发性肝癌与转移性肝癌鉴别中 的临床价值.
- Authors
刘蓬花; 钟 岚; 周长梁; 刘国武; 李建军
- Abstract
Objective: To explore the value of ultrasound contrast ultrasound parameters combined with serum alpha-fetoprotein (AFP) and secreted protein Dikkopf-1 (DKK 1) to identify primary liver cancer (PLC) from metastatic liver cancer (MLC). Methods: 92 PLC patients (PLC group) and 95 MLC patients (MLC group) who were admitted to our hospital from February 2020 to December 2022 were selected, all patients underwent contrast-enhanced ultrasound examination and serum AFP and DKK1 levels were detected. The value of contrast-enhanced ultrasound parameters combined with serum AFP and DKK1 in identifying PLC and MLC was analyzed by receiver operating characteristic (ROC). Results: Initiation time, Enhancement rate and 50% tilt rate in PLC group were lower than those in MLC group (P<0.05), and the peak time, Strengthing strength, serum AFP and DKK1 levels were higher than those in MLC group (P<0.05). The area under the curve of initiation time, Enhancement rate, 50% tilt rate, peak time, Strengthing strength, AFP and DKK1 in differential diagnosis of PLC and MLC was 0.725, 0.655, 0.716, 0.697, 0.761, 0.695 and 0.754 respectively, and the area under the curve identifying PLC from MLC was 0.882, higher than the identification alone. Conclusion: The combination of Ultrasound contrast parameters and serum AFP and DKK1 has high efficiency in the identification of PLC and MLC, better than imaging alone or serum index identification.
- Publication
Progress in Modern Biomedicine, 2024, Vol 24, Issue 7, p1359
- ISSN
1673-6273
- Publication type
Article
- DOI
10.13241/j.cnki.pmb.2024.07.031