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- Title
Clinical Effect of the Custom Tumor Yype Artificial Joint Replacement in Treatment of Giant Cell of Bone Tumor of Long Bones of Limbs in Campanacci' s Level III of Patients.
- Authors
XU Da; YANG Zuo-zhang; ZHANG Jing; WANG Shao-yun; YUAN Tao; ZHANG Jin-yu; CHEN Yanjin; YANG Yi-hao
- Abstract
Objective To discuss the clinical effect and adverse reaction of resection of tumor segment and custom tumor type artificial joint replacement in treatment of giant cell of bone tumor of long bones of limbs in Campanacci' s level III patients. Methods Twenty-nine patients with giant cell tumor of bone in large joints of limbs were diagnosed by objective biopsy and treated by tumor segment resection and custom artificial joint replacement between January in 2004 to January in 2014 at Yunnan Province Cancer Hospital. There were 14 male and 15 female patients, aged from 19 to 85(39.66 on average). The location of tumor in patients was: proximal humerus in 6 cases, the upper segment of femur in 5 cases and the lower segment of femur in 15 cases, the proximal tibia with 6 cases. The Campanacci' s Level was III. We resected the pathological bone and soft tissue out of the tumor boundary in treatment, and truncated bone on surface at 3 to 5 cm to the edge of tumor, and installed artificial prosthesis for reconstruction of the function of human joint. The prosthesis and the interface of host bone were fxied by bone cement fixed technique. The medial head of gastrocnemius muscle transposition was used to repair the soft tissue of proximal tibial of patients underwent the poximal tibial tumor resection. MSTS limb salvage scoring system was used to evaluate the function of patients after treatment. Results The followed up time was 1 to 83 months(36.62 months on average) in 29 patients. I period healing of the operation incision was in 28 patients had, and sinus was formed at the tip of the drainage tube was found in one patient, and the wound were healed after Debridement. The MSTS score in patients was 12 to 27, 23.10 on average. The limb function were excellent in 16 patients, good in 11 patients, moderate in 1 patient and poor in 1 patient, the rate of excellent-good is 93.10%. All cases had no local recurrence, but one was died of lung cancer with metastasis after 2 years. Conclusions The resection of tumor segment and custom artificial joint replacement can be used as limb salvage treatment for giant cell tumor of bone in Campanacci's level III patients. The correct selection of indication, designing individualized prosthesis, good intraoperative fixation and appropriate soft tissue reconstruction can prevent complications and achieve good clinical efficacy.
- Subjects
SURGICAL excision; GIANT cell tumors; BONE cancer; PROSTHETICS; SKELETAL muscle
- Publication
Journal of Kunming Medical University / Kunming Yike Daxue Xuebao, 2015, Vol 36, Issue 2, p43
- ISSN
2095-610X
- Publication type
Article